A small percentage of pancreatic tumors arise in the hormone-producing glands of the pancreas and give rise to a less aggressive type of cancer. Early detection of pancreatic cancer is difficult because the disease generally presents no symptoms until the tumor grows large or spreads to other parts of the body.
Fred Hutchinson Cancer Center researchers are studying the unique biology of pancreatic cancers to discover what makes these tumors so deadly, and they are translating their findings into new therapies that target the tumors’ defenses.
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Researchers and Patient Treatments | Clinical Trials | Pancreatic Cancer Research
Our Pancreatic Cancer Researchers
Our interdisciplinary scientists and clinicians work together to prevent, diagnose and treat pancreatic cancer as well as other cancers and diseases.
Patient Treatment and Care
At Fred Hutch, our interdisciplinary teams work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Our aim is to provide patients access to advanced treatment options while getting the best cancer care.
Pancreatic Cancer Clinical Trials
Clinical research is an essential part of the scientific process that leads to new treatments and better care. Clinical trials can also be a way for patients to get early access to new cutting-edge therapies. Our clinical research teams are running clinical studies on various kinds of pancreatic cancer.
Pancreatic Cancer Research
Our scientists are working to pinpoint the genetic factors that spur the development and progression of pancreatic cancer, including its high metastatic drive. As we uncover the disease’s biomarkers, we’re opening the door to earlier detection. We’re also discovering the unique properties that make these tumors so resistant to traditional forms of treatment. Our lab-based findings translate to clinical trials of promising new treatments — from targeted drugs to genetically modified immune-cell therapies.
Targeting Tumor Defenses
Our researchers collaborate with colleagues around the country to understand the biological context of pancreatic tumors. Nearby immune cells, blood vessels, and a tumor's internal pressure can make it resistant to treatment. We’re developing new therapies that target a tumor's defenses. They include treatment strategies that combine cancer-killing drugs with new agents that disrupt the tumor’s supportive tissues or alter the anti-cancer immune response.
New Targets for Tailored Treatment
A deeper understanding of the genetic changes found within various types of pancreatic cancer, and how these changes promote disease development and progression, could reveal new treatment targets. Our scientists are working to improve patient care by identifying specific tumor vulnerabilities and developing new therapies to better target them.
We are also part of a nationwide effort that aims to deliver the promise of precision medicine to patients with pancreatic cancer. With our collaborators, we are testing a fluid new form of a clinical trial in which pancreatic cancer patients receive the experimental treatment that researchers believe will best target their tumor. If needed, patients can later transition to other treatments that take aim at their tumor’s shifting biology.