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How protective antibodies get in malaria’s way
Fred Hutch researchers’ structural insights help reveal weak spot in parasite’s mode of attack, could guide vaccine design
Laying the groundwork for a new cancer-preventive vaccine
Fred Hutch scientists garner large NCI award to uncover secrets of immune response to virus behind Kaposi sarcoma
Going straight to the source in defense against infant RSV
New anti-idiotype antibody a first step in possible strategy to build infant immunity during vulnerable window
Infectious disease experts propose trials network dedicated to immunocompromised patients
ImmunOptimize workshop convened stakeholders across disciplines to brainstorm infectious disease clinical trials network designed to serve people with weakened immune systems
Engineered HSV can trigger genetic chain reaction, rejigger HSV genes during co-infection
Proof-of-concept work raises hope that ‘gene drive’ could one day form basis of curative gene therapy for herpes
Jennifer Doudna: ‘Curiosity-driven, fundamental science’ underpins Nobel Prize-winning work
CRISPR pioneer spoke at inaugural Fred Hutch President’s Seminar, outlined goals for gene-editing technology
Vaccine trial volunteer works to empower her community, end HIV
Community Advisory Board member Tasia Baldwin helps raise awareness of the ongoing HIV epidemic and how individuals can get involved in research aimed at ending it
Zeroing in on vaginal microbes that most increase HIV risk
Signature combination of BV bacteria and immune proteins associated with highest risk could help guide prevention
A quarter century of lifesaving discoveries in prostate cancer
Pacific Northwest Prostate Cancer SPORE insights have transformed patient care and understanding of prostate cancer biology, supported drug discovery worldwide
‘Black hole’ formed by aging cells hobbles key immune organ’s function, regeneration
Collaborative project reveals non-functional cells that accumulate in aging thymus
Finding a rare bile duct cancer’s weaknesses
DOD and Cholangiocarcinoma Foundation awards will help Dr. Debraj Boila reveal genetics, drug targets of intrahepatic cholangiocarcinoma
What doesn’t kill you makes you stronger: Bacteria that withstand fungal ‘bully’ gain resistance to last-resort antibiotic
Study shows that microbial competition over magnesium may improve bacterium’s antibiotic resistance and stymie treatment
Secret to tamping down GVHD may lie in microbial genetics
Preclinical bone marrow transplant study shows donor immune cells that target recipient microbiome can influence GVHD severity
Taking a frothy risk to advance gene therapy
Fred Hutch scientists hope foam could be a cost-reducing, access-enhancing vehicle for delivering future gene therapies
Tackling an aggressive form of pancreatic cancer
Dr. Stephanie Dobersch awarded American Cancer Society Fellowship to study genetics of basal pancreatic adenocarcinoma
Bridging the gap between cancer drug target and cancer drug
Fred Hutch RNA-translation expert Dr. Andrew Hsieh receives Harrington Scholar-Innovator Award to develop experimental compound into anti-cancer drug
Mutant’s partner in crime could be target for future cancer therapy
Fred Hutch scientists discover a new player — and possible drug target — in a critical biological process that’s skewed in tumors with certain mutations
Targeted new approach and computational tools reveal lung cancer subtypes hiding in patterns in cell-free DNA
Innovative strategy a step toward liquid biopsy to detect, monitor aggressive small cell lung cancer
Revealing how cancer cells cooperate — and how to stop them
$1 million from Kleberg Foundation will support Dr. Kevin Cheung’s investigations into the collaborative strategies tumors use to spread and resist treatment
New techniques, collaborations push patient-focused precision oncology forward
$5.4M NCI award supports Dr. Chris Kemp’s multi-disciplinary discovery platform for cancer-therapy targets