What do you mean by skin cancer?
As with many cancers, there are different subtypes of skin cancer.
Non-melanoma skin cancers like basal cell carcinoma and squamous cell carcinoma (named for the skin cells on the top layer of your skin) are the most common cancers in the country, afflicting an estimated 3.3 million people per year. These cancers are very treatable and much less likely to metastasize, that is, spread to other parts of the body.
Melanomas are different, arising from another cell type (melanocytes — the cells that make pigment). These cancers are more serious and again, there are subtypes, including rare occurrences of ocular melanoma (which affects the eyes) or mucosal melanoma which affects the inside of the nose, mouth, throat, genital or anal area.
Most melanomas are cutaneous, which means they affect the skin, often the skin that’s exposed to the sun. Ultraviolet rays are a major cause of cutaneous melanoma — the radiation from the sun damages your DNA; that’s why skin cancer prevention focuses so much on covering up and using sunscreen.
The American Cancer Society, or ACS, estimates there will be around 100,640 new melanoma diagnoses in the U.S. in 2024, with nearly 8,300 people expected to die from it. Wondering what skin cancer looks like? Check out these tips from ACS, the American Academy of Dermatology, the National Cancer Institute and various patient platforms.
Who’s most at risk for skin cancers?
Well-known factors that can bump your risk include a high number of moles; fair skin and light-colored hair and eyes; a family history of the disease; a weakened immune system; being older or having skin that’s susceptible to burning or tanning.
While there’s little you can do about family history or fair skin, there are still actions you can take to reduce the risk of melanoma. Avoiding sunburn is the big one.
A history of sunburn significantly increases the risk of developing melanoma, particularly if you have experienced severe sunburns that resulted in blistering, according to Fred Hutch dermatologist Song Park, MD, who treats patients with melanoma.
“Even one severe sunburn, especially in childhood or adolescence, can more than double your risk of melanoma,” she said, pointing to a large study published in 2016.
Fred Hutch epidemiologist Margaret M. Madeleine, MPH, PhD, concurred: “With melanoma, the most important sun exposure may be during childhood,” she said.
But that doesn’t mean the horse is already out of the barn for those who tanned as teens.
“It’s not only cumulative exposure but current exposure that increases one’s risk,” Madeleine said, adding that while melanoma rates have dropped in teens and young adults thanks to cancer prevention messages, they’re still increasing in people who are older.
Certain medications can also make you tan or burn more easily. If you’re in cancer treatment, check with your care team to make sure the medications you’re taking don’t cause unintentional harm.