Translational Science and Therapeutics Jobs

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

A paid postdoctoral position is available immediately in The Grady Lab at Fred Hutch. The applicant will perform data-driven research using state-of-the-art molecular and cell biology tools across various research projects to advance translational research in epi/genomics of gastrointestinal cancers. Adherence to principles of reproducible research, motivation to keep up with cutting-edge molecular and cell biology research technologies, data analysis tools, and willingness to team-work in multi-disciplinary research programs will be vital to success in this position. The laboratory is situated in the Translational Science & Therapeutics Division at Fred Hutch.

Responsibilities

• Conducting data-driven research: Engaging in scientific research using cutting-edge molecular and cell biology tools to investigate epi/genomics aspects of gastrointestinal cancers
• Experimental design: Planning and designing experiments that align with the research objectives and contribute to the advancement of translational research.
• Data collection and analysis: Performing experiments, gathering data, and utilizing bioinformatics and data analysis tools to analyze and interpret research findings.
• Literature review: Staying abreast of the latest developments in molecular and cell biology research, epi/genomics, and gastrointestinal cancers to inform and enrich the research project.
• Collaboration and teamwork: Collaborating effectively with other members of the lab and participating in multi-disciplinary research programs to foster a team-oriented research environment.
• Reproducible research: Ensuring the adherence to principles of reproducible research, maintaining detailed documentation of methodologies, data, and results.
• Presentation and communication: Effectively communicating research findings through presentations at lab meetings, seminars, conferences, and preparing scientific publications.

Qualifications

MINIMUM QUALIFICATIONS:

• The successful candidate will have a PhD in molecular or cell biology, or related field.
• Established experience cell biology and molecular biology.
• Experience in standard techniques in molecular and cell biology, including 2D and 3D cancer cell line and organoid tissue culture, gene editing, PCR, western blotting, immunohistochemistry, flow cytometry, next generation sequencing (ChIP-Seq and bisulfite Seq is desirable), etc.

PREFERRED QUALIFICATIONS:

• Familiarity with and basic skills in computational biology analyzing data from RNA seq, genome-wide DNA methylation and multi-omics is desirable.
• Experience with mouse models is desirable.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The annual base salary range for this position is from $77,976 to $150,000 and pay offered will be based on experience and qualifications.  

This position may be eligible for relocation assistance.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).  

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

The Clurman lab (https://research.fredhutch.org/clurman/en.html; TST and Human Biology Divisions) works at the intersection of two fields: cell cycle control and the ubiquitin system. While our work focuses on both tumorigenesis and fundamental regulatory mechanisms in normal biology. Our overall goal is to apply new mechanistic insights to understand cancer development and develop new therapeutic strategies.  

Responsibilities

We are seeking a highly qualified and motivated Postdoctoral Fellow to study the ubiquitin pathway in various aspects cell division and tumorigenesis. This work will focus on tumor suppression by the Fbw7 ubiquitin ligase, which targets a network of oncoproteins for degradation, including Myc, Notch, and cyclin E. This work will encompass a broad array of approaches, including cell and molecular biology, gene targeting in mice and human cells, and large-scale genomics and proteomics. We value lab members who are highly collaborative but can also independently develop and guide research projects.  

Qualifications

• PhD, M.D., or M.D., Ph. D (or equivalent degree) in cell and molecular biology, cancer biology, biochemistry, or a related field.
• Broad expertise in cell and molecular biology methods and the ability to master new techniques and approaches.
• Experience with genetically engineered mouse models of cancer is highly preferred.
• Excellent written and communication skills.
• Record of productive and rigorous research, including at least one primary publication in a peer-reviewed journal.
• Ability to independently plan, conduct, and analyze research.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The annual base salary range for this position is from $77,976 to $150,000 and pay offered will be based on experience and qualifications.

This position may be eligible for relocation assistance. 

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

The Ring Lab of Synthetic and Systems Immunopharmacology is located within the Translational Science and Therapeutics Division and is a member of the Immunotherapy Integrated Research Center (IIRC). Their primary focus is on developing unique and first-in-class therapeutic drugs for cancer immunotherapy using cutting-edge protein engineering with directed evolution. The lab has developed therapeutics that are currently in clinical trials, such as ST-067 (a "decoy-resistant" IL-18), MDNA-11 (CD122-biased IL-2), and ALX-148/evorpacept (an ultra-high affinity SΙRPα decoy). Moreover, the Ring Lab is actively working on developing platforms for identifying new targets in cancer immunotherapy. These technologies include the REAP platform for discovering autoantibodies in patient samples, and high-throughput techniques in synthetic antibody engineering and proteogenomics to pinpoint new tumor antigens.

Responsibilities

The Ring Lab is recruiting a Post-Doctoral Research Fellow with expertise in immunology, systems/computational biology, and/or protein engineering. This position will involve research projects that investigate the relationship between patient autoantibodies and health and disease outcomes. At the core of these programs is the REAP autoantibody profiling technology, which provides unprecedented levels of detail about the "autoantibody reactome" present in patient blood and tissue samples. Researchers will perform the very first "autoantibody-wide association studies" to pinpoint how specific autoantibody reactivities impact disease biology, analogous to but independent from the effect of genetic variation. This entirely new research program is poised to identify novel therapeutic targets for a range of indications including cancer, autoimmune disease, inflammatory conditions such as IBD, infectious disease, and neurodegeneration.

The ideal candidate will be a highly-curious, motivated, independent, and collaborative research scientist keen to explore new areas of biology and therapeutic development. They will work closely with Dr. Ring, lab manager Alison Notestine, external collaborators, and other members of the Ring laboratory to execute highly-multidisciplinary studies. Furthermore, they will have the opportunity and responsibility to contribute to the preparation of research reports and scientific manuscripts, as well as present at scientific conferences and symposiums. The Ring lab welcomes candidates with a diverse range of career aspirations and has a track-record of supporting trainees to pursue careers in academia, biotech/pharma, life-science investing, and consulting.

Qualifications

MINIMUM QUALIFICATIONS:

• MD or PhD in a related field
• Broad experience in molecular and cell biology methods and the ability to master new techniques and approaches
• Excellent verbal and written communication skills
• A team player with strong aptitude for collaboration

PREFERRED QUALIFICATIONS:

• Experience in one or more of the following areas:
  • Immunology
  • Systems biology/bioinformatics
  • Single cell transcriptomics/proteogenomics
  • Protein engineering/directed evolution with yeast, phage, or mRNA/ribosome display technology
• Experience with mouse models is desirable

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The annual base salary range for this position is from $77,976 to $150,000 and pay offered will be based on experience and qualifications.

This position may be eligible for relocation assistance.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

Responsibilities

The Geoff Hill Lab, in Seattle’s Fred Hutchinson Cancer Center Translational Science & Therapeutics Division, is recruiting a Post-Doctoral Research Fellow with expertise in transplant immunology and/or immunotherapy. The candidate will have the opportunity to contribute to multiple NIH funded research programs, including studies defining the mechanisms of cancer-specific immunity versus immune escape and pathogen-specific immunity after adoptive cell therapy. There are also active programs defining  mechanisms of, and innovative treatment paradigms for immune toxicity (e.g. graft-versus-host disease and cytokine release syndrome) after stem cell transplantation and adoptive cell therapy.

Qualifications

MINIMUM QUALIFICATIONS:

• MD or PhD in a related field
• A strong foundation in immunology and cell biology
• A track record of productive research

 PREFERRED QUALIFICATIONS:

•  Expertise in cellular immunology and a background in bone marrow/stem cell transplantation and/or immunotherapy

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The annual base salary range for this position is from $77,976 to $150,000 and pay offered will be based on experience and qualifications. This position may be eligible for relocation assistance. 

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

The Clurman Lab (https://research.fredhutch.org/clurman/en.html; TST and Human Biology Divisions) works at the intersection of two fields: cell cycle control and the ubiquitin system. While our work focuses on both tumorigenesis and fundamental regulatory mechanisms in normal biology. Our overall goal is to apply new mechanistic insights to understand cancer development and develop new therapeutic strategies.

Responsibilities

We are seeking a highly qualified and motivated Postdoctoral Fellow to study the molecular control of the cell cycle in both normal and neoplastic contexts. This work will focus on cyclin E-CDK2 activity and regulation in cancer and in normal cells. This includes studies of new substrates, understanding how cyclin E activity and regulatory mechanisms may be therapeutically leveraged, and how cyclin E promotes tumorigenesis. One area of current focus includes studies of head and neck squamous cell cancer.  This work will encompass a broad array of approaches, including cell and molecular biology, gene targeting in mice and human cells, and large-scale genomics and proteomics. We value lab members who are highly collaborative but can also independently develop and guide research projects.  

Qualifications

• PhD, M.D., or M.D., Ph. D (or equivalent degree) in cell and molecular biology, cancer biology, biochemistry, or a related field.
• Broad expertise in cell and molecular biology methods and the ability to master new techniques and approaches.
• Experience with genetically engineered mouse models of cancer is preferred.
• Excellent written and communication skills.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The annual base salary range for this position is from $77,976 to $150,000 and pay offered will be based on experience and qualifications.

This position may be eligible for relocation assistance.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington. 

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

The Research Administrator II will work under the direction of a Research Administration Manager and will be part of a team of Research Administrators and an Administrative Coordinator which provides a network of peer resources and team environment in performing daily responsibilities, partnering with principal investigators (PIs) and interfacing with other departments as needed to provide research administration. 

Responsibilities

Fiscal Support

• Serve as Purchasing liaison for some departments in the group, placing and approving orders for office and laboratory supplies and equipment. Create and maintain standing orders for a variety of vendors.
• Working with the PIs, submit annual capital equipment and internal funding requests.
• Submit work orders for lab equipment repairs; procure and schedule outside maintenance when needed.  

Funding Source Administration

• Lead the grant submission process, to include writing and completion of non-technical portions of submission, oversight of institutional signoff, and preparation of JIT materials.
• Perform post award activities, including annual progress report submission and sub-award activation and management.
• Monitor project budgets, ensuring that all financial allocations and expenditures are in accordance with grant/contract guidelines & regulations as well as institutional policies.
• Manage non-sponsored budgets, such as discretionary accounts and gift funds.
• Prepare monthly budget summaries and reports for PIs.
• May assist with some fiscal management aspects of industry-sponsored clinical trials.

Administrative Support

• Maintain faculty documents such as CV, NIH Biosketch, Other Support, and Academic Review & Promotion portfolio materials.
• Perform Human Resources activities, such as on/off boarding, staff recruitment plans, and coordination of annual performance evaluations.
• Manage monthly time and effort reporting for the group.
• Assist the Regulatory Manager with IRB, IACUC, and MUA applications and renewals.
• Special projects and other tasks as assigned.

Qualifications

MINIMUM QUALIFICATIONS:

• HS Diploma or equivalent.
• Two years of relevant experience.
• Advanced proficiency with Microsoft Office/Adobe.
• Working knowledge of Excel formulas and functions such as creating formulas and working with Pivot Tables.
• Ability to edit SharePoint sites or basic web pages.
• Knowledge/prior experience with Enterprise Software Systems.
• Ability to source data from systems and generate customized reports.
• Efficiently planning, organizing, and prioritizing your work as well as that of others.
• Ability to tailor communications to specific audiences.
• Ability to navigate complex internal systems and departments.
• Basic budgetary knowledge (ability to reconcile, manage, report budget information, etc.).
• Basic knowledge of accounting terminology.
• Prior experience or exposure to grant writing/applications including the knowledge of Uniform Guidance and government funding rules.

PREFERRED QUALIFICATIONS:

• Bachelor's Degree.
  
• Prior administrative experience in a research or academic setting.
  
• Proficient in fiscal and budgetary management.
  
• Experience in preparing and managing NIH grants.
  
• Exposure to industry-sponsored clinical trials.
  
• Prior experience with WorkDay, CLICK products, EPIC, and/or OnCore.
  
• Knowledge of bibliographic software, citation management software, web authoring software, and graphing and illustration software.
• Excellent verbal and written English language skills and the ability to communicate effectively with personnel from a variety of levels.
• Proactive, can anticipate needs, and set and meet deadlines.
• Ability to exercise sound judgement and make appropriate decisions.
• Capable of working autonomously to complete assigned tasks with minimal supervision/direction.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The hourly pay range for this position is from $32.77 to $49.14 and pay offered will be based on experience and qualifications.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months). 

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

The Research Administrator III (RA) is a high-level career position which supports the faculty and lab personnel in the Translational Science and Therapeutics Division by providing support in grants and contract management (Pre- and Post- Award), budget development and monitoring, regulatory administration, and general day-to-day operations of the program faculty. The financial portfolio is comprised of various sources of NIH, foundation, industry, professional society, internal pilot, subawards, and institutional support and includes regulated activities.

This role is part of a team of Research Administrators and Administrative Coordinators which provides a network of peer resources and team environment supporting the program faculty. The position will work under the direction of the Program Operations Director and will act independently in performing daily responsibilities, partnering with program faculty, and interfacing with other departments as needed to provide efficient research administration.

This role will have the opportunity to work partially at our campus and remotely.

Responsibilities

Funding Source Administration

• Responsible for all pre- and post-award operations for each faculty in their assigned portfolio, providing operational oversight of the administrative implementation and financial management of research studies and associated agreements within the Program.
• Manages grant submissions and post award activity by conducting tasks such as:
  • Preparing grant application budgets
  • Completing/collating of all technical/non-scientific steps and assigned technical or scientific portions of funding/grant submissions
  • Review budgets, identify discrepancies and provide recommendations to the PI on scenarios to resolve the issues with appropriate stakeholders
  • Identify/forecast personnel and other resource requirements (including long-range forecasting across multiple budget years)
  • Working with faculty to respond to requests from other departments and external organizations
• Perform post-award activities, including annual progress report submission and sub-award activation and management.
• Manage non-sponsored budgets, such as discretionary accounts and gift funds.
• Prepare monthly budget summaries and reports for PIs.
• May assist with fiscal management aspects of industry-sponsored clinical trials.

Fiscal Support

• Develop, monitor, track and forecast the budgets for a portfolio of projects with multi-variable aspects. (multi-site, sub awards, milestone-based budgets etc.).
• Monitor spending for adherence to grant guidelines and policies, as well as internal policies.
• Develop, run, and analyze reports to identify funding issues and develop recommendations.
• Develop customized report formats to share information with each faculty member and for broad audiences across the organization.

Regulatory Support

• Prepare non-scientific portions of regulatory applications/submissions related to human subject’s research.
• Identify missing regulatory components that are required and resolve issues to ensure successful submission, modification, or renewal.
• Serve as a central point of contact to answer questions and facilitate solutions.
• Prepare/consult/advise PIs and maintain Data/Material Use Agreements and other data compliance documentation.

Administrative Support

• Identify administrative needs for the department or PIs; prioritize and ensure related tasks are completed.
• Delegate appropriate tasks to junior RAs and/or Administrative Coordinator and follow up as necessary.
• Oversee the management of projects including occasional event planning and special work groups.
• Communicate with other departments/entities on PI’s behalf.
• Other duties as assigned.

Qualifications

MINIMUM QUALIFICATIONS:

• Bachelor’s degree or 3 years relevant experience
• Minimum of 1 year experience managing federal and/or non-federal sponsored research.
• Advanced proficiency with Microsoft Office/Adobe
• Working knowledge of Excel formulas and functions such as creating formulas and working with Pivot Tables
• Ability to edit SharePoint sites or basic web pages
• Knowledge/prior experience with Enterprise Software Systems
• Ability to source data from systems and generate customized reports
• Efficiently planning, organizing, and prioritizing your work as well as that of others
• Ability to tailor communications to specific audiences
• Ability to navigate complex internal systems and departments
• Basic budgetary knowledge (ability to reconcile, manage, report budget information, etc.)
• Basic knowledge of accounting terminology
• Knowledge of relevant regulatory guidelines such as IRB, IACUC, MUA
• Prior experience or exposure to grant writing/applications

PREFERRED QUALIFICATIONS:

• Previous recent grants and contract management experience of more than 3 years.
• Able to understand, interpret and provide guidance relating to notices of award and terms/conditions for sponsored research.
• Budget development and management for multiple types of funding mechanisms (NIH, Foundation, Industry, and pilot funding.)
• Competency working with individuals in remote work setting
• Strong organizational and problem-solving skills and the ability to manage competing priorities.
• Excellent verbal and written communication skills and the ability to communicate effectively with personnel from a variety of levels.
• Ability to exercise sound judgement and make appropriate decisions.
• Proactive, can anticipate needs, and set and meet deadlines.
• Capable of working autonomously to complete assigned tasks with minimal supervision/direction.
• Prior administrative experience in a research or academic setting.
• Multi-project grants management experience with a wide variety of funding sources.
• Working knowledge of medical terminology and familiarity with Human Subjects Protection.
• Exposure to industry-sponsored clinical trials.
• Prior experience with WorkDay, CLICK products, EPIC, and/or OnCore.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The annual base salary range for this position is from $82,847 to $124,238, and pay offered will be based on experience and qualifications.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months). 

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

The Silberstein Lab is looking for a Research Technician I. The main goal of the laboratory is to combine basic stem cell biology and clinically relevant murine models in order to develop new therapeutic approaches to promote hematopoietic stem cell function in bone marrow failure and to enhance hematopoietic reconstitution after bone marrow transplantation. We are particularly interested in using microenvironment-derived molecules as drugs or therapeutic targets and have identified several novel niche factors using proximity-based single cell analysis as a discovery strategy (for details, please see Silberstein et al, Cell Stem Cell 2016, Goncalves, Silberstein et al, Cell 2016).

Please provide a cover letter addressed to Dr. Silberstein explaining why you would like to join the Silberstein lab.

Responsibilities

A successful candidate will work as a part of the highly collaborative team and focus on conducting animal experiments which involve stem cell transplantation, fluorescently activated cell sorting/analysis and molecular studies of stem cells/progenitors. They will also share responsibility for murine colony maintenance.

The incumbent will be part of a Stem Cell and Gene Therapy Program at the Fred Hutch and interact closely with other laboratories within the Program (Kiem, Adair, Bernstein, Hadland, Doulakov) and those within Integrated Immunotherapy Research Center (Dudakov, Headley).

Other duties as assigned.

Qualifications

MINIMUM QUALIFICATIONS:

• Bachelor's degree in a biological science and some research experience or laboratory knowledge. Must have scientific knowledge in the area of study and basic laboratory skills. Independent research experience in addition to school lab experience is also necessary.

PREFERRED QUALIFICATIONS:

• Strong interest in stem cell research/bone marrow disorders.
• Excellent written and verbal communication skills.
• To be successful in this position, the technician must be highly motivated, have a high level of initiative, work carefully, and keep detailed records. They must also be capable of working independently in a teamwork environment and have excellent interpersonal and communication skills.
• Previous experience working with murine models is not essential, but one of the chief responsibilities will involve handling the animals daily and performing standard procedures.
• Some multi-parameter flow cytometry experience (undergraduate research or post-graduation).
• Candidates considering medical/graduate schools are encouraged to apply.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The hourly pay range for this position is from $22.87 to $32.56 and pay offered will be based on experience and qualifications.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months). 

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

The focus of research conducted in Dr. William Grady’s laboratory in the Translational Science & Therapeutics Division of the Fred Hutchinson Cancer Center is the study of the molecular and cell biology of gastrointestinal cancer as well as the role of genetic and epigenetic alterations in cancer.

Responsibilities

Under general supervision of the PI and senior post-doctoral fellows in the lab, the Research Technician will perform varied support functions requiring knowledge and skills specific to the research study.

Job responsibilities will include the following:

• Collection and processing of human and mouse tissue samples
• DNA, RNA extraction from fresh frozen or formalin fixed paraffin-embedded human tissue samples
• Proficient with real-time PCR technology
• Protein extraction, cell fractionation, western blot, and immunoprecipitation
• Responsible for the organization of specimen inventory in short-term and long-term storage
• In vitro cell culture experiments
• Mouse husbandry/colony management with transgenic and conditional knock-out mice
• Maintain a database used for organizing the current inventory and tracking the location of specific information/specimens
• Collect and analyze data
• Monitor adherence to study protocol
• Inform PI of deviations from study protocol
• Attend project meetings
• Keep detailed records for experiments
• Maintain a high level of accuracy for all work
• Perform other duties as assigned

Qualifications

MINIMUM QUALIFICATIONS:

• A Bachelor’s Degree in one of the biological sciences with strong background in molecular biology and cell biology, or equivalent combination of education and experience
• Demonstrated scientific knowledge in the area of study
• Demonstrated basic laboratory skills

PREFERRED QUALIFICATIONS:

• Highly self-motivated and trustworthy.
• Willing to take up new skills and responsibilities, follow instructions, and capable of working independently in a teamwork environment.
• Have excellent interpersonal and communication skills.
• Competency with Microsoft Excel, Word, and PowerPoint, and Adobe Photoshop

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The hourly pay range for this position is from $22.87 to $32.56 and pay offered will be based on experience and qualifications.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months). 

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

The Fong lab is seeking an experienced Research Technician I or Research Technician II to work in a collaborative environment leading research on cancer immunotherapy. The focus of our lab is to unravel the mechanisms of response and resistance to cancer immunotherapy. In addition, candidates with significant expertise in antibody-medicated cell enrichment procedures, flow cytometry, and cell cryopreservation will be viewed as highly favorable candidates.

Responsibilities

This is expected to be a long-term position and the successful applicant will help oversee the day to day running of the mouse colony in collaboration with senior graduate laboratory members. The candidate will also contribute to multiple projects studying the dynamic interactions governing the generation of anti-tumor immunity and apply this knowledge toward developing novel approaches for the study and treatment of cancer. The technician will be closely involved in research projects using in vivo murine models of transplantation, cancer patient-derived samples, and engineered cell therapy models combined with single cell, spatial, and computational approaches to study the dynamics of an immune response.

The successful applicant will ideally have a basic knowledge of immunology and colony management with previous experience in laboratory murine handling, genotyping, and cell culture, and be capable of maintaining detailed laboratory records.

In conjunction with the senior Research Technicians, key duties will include:

• Oversight and maintenance of a large murine colony
• Scheduling and coordinating experiments with other lab members and collaborators
• Maintenance and inventory of laboratory reagents, stocks, and media
• Monitoring experimental animal well-being
• Supporting complex experimentation

Qualifications

MINIMUM QUALIFICATIONS:

• Research Technician I:
  • Bachelor’s degree in related scientific field or equivalent combination of education and experience
  • Demonstrated scientific knowledge in the area of study
  • Demonstrated basic laboratory skills
• Research Technician II:
  • Bachelor’s degree in related scientific field or equivalent combination of education and experience
  • 2 years of experience working in a lab outside of school coursework

PREFERRED QUALIFICATIONS:

• A Master’s degree in a related field may substitute for two years of professional lab experience.
• Demonstrated ability to independently provide colony management with minimal supervision.
• Extensive hands-on mouse husbandry experience.
• Demonstrated mouse handling skills.
• Experience with murine models and murine colony maintenance including complex cre-flox systems.
• Demonstrated strong organization skill and attention to detail.
• Demonstrated ability to perform PCR genotyping.
• Experience with basic injections. (e.g., IP, SC, gavage)
• Basic understanding of animal welfare and ethics.
• Aseptic culture technique.
• A basic understanding of and prior exposure to flow cytometry.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Research Technician I: The hourly pay range for this position is from $22.87 to $32.56 and pay offered will be based on experience and qualifications.  
Research Technician II: The hourly pay range for this position is from $26.48 to $37.70 and pay offered will be based on experience and qualifications.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months). 

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

The Geoff Hill Lab, in Fred Hutch's Translational Science & Therapeutics Division, is recruiting a Scientist / Senior Scientist with expertise in transplant immunology and/or immunotherapy. The candidate will have the opportunity to contribute to multiple NIH funded research programs, including studies defining the mechanisms of cancer-specific immunity versus immune escape and pathogen-specific immunity after adoptive cell therapy. There are also active programs defining mechanisms of, and innovative treatment paradigms for immune toxicity (e.g. graft-versus-host disease and cytokine release syndrome) after stem cell transplantation and adoptive T cell therapy. 

Responsibilities

Responsibilities for this highly-skilled laboratory scientist will include: designing, performing and analyzing experiments, troubleshooting technical issues and mentoring junior lab members. The successful candidate will also be expected to contribute to the preparation of manuscripts and grant proposals and oversee large programs that include collaborating laboratories.

Qualifications

MINIMUM QUALIFICATIONS FOR STAFF SCIENTIST:

• MD or PhD degree in Immunology or related field.
• Four (4) or more years of post-Ph.D. laboratory experience. 

MINIMUM QUALIFICATIONS FOR SENIOR STAFF SCIENTIST:

• MD or PhD degree in Immunology in related field.

• Minimum 5 years of experience at Fred Hutch or, have a minimum of 5 years of unique expertise and extensive experience at other academic institutions or in private industry.

PREFERRED QUALIFICATIONS:

• Working knowledge of transplant and cancer immunology.
• Experience with technologies used in the lab, including mouse models, high parameter flow cytometry and single-cell RNA sequencing.
• Technical experience includes:
  
  • Cellular immunology, including high dimensional flow cytometry
  • Mouse models of experimentation
  • Correlative human immunology analyses
  • RNA-sequencing
• Track record of high impact publications and some prior success in grant applications.
• Excellent organizational skills, attention to detail and reliable record-keeping.
• Ability to design and execute protocols, and work independently including experimental troubleshooting.
• Effective communication and interpersonal skills for working with other lab members and productive interactions with collaborators.
• Applicants should be highly-motivated scientists

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The annual base salary range for the Senior Staff Scientist is from $94,033 to $212,030 and pay offered will be based on experience and qualifications. 

The annual base salary range for the Staff Scientist position is from $82,123 to $185,000 and pay offered will be based on experience and qualifications. 

This position may be eligible for relocation assistance.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (up to 13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 12 months for professor track faculty, up to 6 months for other scientific staff).