Bryan Mayer, PhD
Senior Staff Scientist
Vaccine and Infectious Disease Division, Fred Hutch
Research interests include analysis of immune responses to vaccine candidates, study design for challenge studies, statistical methods for biological assays, mathematical models of viral load kinetics, and pharmacokinetic/pharmacodynamic modeling.
Education
University of Michigan, 2012, PhD (Epidemiology)
University of Michigan, 2008, MS (Biostatistics)
Michigan State University, 2006, BS (Mathematics)
Research Interests
Design and analysis for pre-clinical challenge studies
Mathematical modeling (pharmacokinetics, viral load kinetics)
Quality control and standardization of biological assays
Assessment of vaccine Immunogenicity in early phase clinical studies
Current Projects
Pharmacokinetic modeling of antibodies to prevent transmission of HIV
Analysis of innate immune responses generated from HIV vaccine candidates
Dose-response modeling of antibody concentrations with neutralization potency
Assessment of antibody interaction with viral dynamics of HIV